Diffuse large bcell lymphoma dlbcl is the most common subtype of. Males are slightly more likely to develop hodgkins lymphoma than are. Other mature b cell lymphomas that can arise in the gi tract are burkitt lymphoma bl, follicular lymphoma fl, mantle cell lymphoma mcl. Despite its well known histological and clinical features, hodgkins lymphoma hl has recently been the. Nonhodgkin lymphoma sometimes called nhl, or just lymphoma is a cancer that starts in cells called lymphocytes, which are part of the bodys immune system. Classic hodgkin lymphoma chl is a monoclonal lymphoid neoplasm in most instances derived from b cells composed of mononuclear hodgkin and multinucleated hodgkin reedsternberg hrs cells residing in an infiltrate containing a variable mixture of nonneoplastic small lymphocytes, eosinophils, neutrophils, histiocytes, plasma cells, fibroblasts and collagen fibers who classification of tumours of haematopoietic and lymphoid tissues, 4th edition, lyon 2008. The two major types of lymphoma are hodgkin lymphoma hl and nonhodgkin lymphoma nhl. About marrow, blood and blood cells the information in this section about normal blood and marrow may. Follicular lymphoma fl is a heterogeneous disease, and there are many different subgroups, such as in terms of age of onset, involved organ especially. Hodgkins lymphoma is most often diagnosed in people between 15 and 30 years old and those over 55. Aggressive bcell lymphomasfrom morphology to molecular.
Nonhodgkin lymphoma and hodgkin lymphoma are the two main types. In the united states in 20, about 9,290 persons were expected to be diagnosed with hodgkin lymphoma. Nonhodgkin lymphoma pathology, imaging, and current. Jobs, fellowships, conferences, cases, cme related chapters. Hodgkin lymphoma hematology and oncology merck manuals. Lymphoma is a general name for a group of cancers that affect the lymphatic system. More likely than hodgkin lymphoma to be extranodal, disseminated, involve peripheral blood, bone marrow, gi, skin or cns less likely than hodgkin lymphoma to have b symptoms only 20% versus 40% in hodgkin lymphoma or have mediastinal involvement except that mediastinal involvement is common in lymphoblastic and mediastinal large b cell lymphoma. Having a blood relative with hodgkins lymphoma or nonhodgkins lymphoma increases your risk of developing hodgkins lymphoma.